Erythema Multiforme

Erythema multiforme

Erythema means Redness of skin & multiforme means macules ,papules ,or maculopapular ,vesicles like lesion in many form or multiform (lesion between lesion, e.g. Bulls eye or Iris lesion /target like lesion)

Erythema multiforme

 

Definition of erythema multiforme :

Erythema multiforme is a skin disease which appeared as redness of skin & maculopapular lesions in multiform on dorsum of hand & forearm commonly including target lesions caused by hypersensitivity reaction .

Types of Erythema multiforme :

-Erythema multiforme major

-Erythema multiforme minor

Location of  erythema multiforme:

Commonly located on dorsum of hand .This region can be most prominent site to do diagnosis easily.but can appear in dorsum of feet,leg ,trunk,(mucus membranes like lips,oral mucosa,vagina) also

 

Symptoms of erythema multiforme

Erythema multiform minor:Typical Target lesions appeared or raised oedematous popular lesions are found spreadly or acrally

Erythema multiforme major :

Typical Target lesions plus involvement of one or more mucous membrane affected (i.e- oral mucosa,lips,vagina & etc.)

 

Most affected person’s ages are

– Young adult

-child age

Causes of erythema multiforme:

Some Medication can be attributed for occurring this disease because every drugs have side effects as low or more .But physicians are almost practically proved that some drugs are highly prone to side effect such as-

-Antibiotics:

* Penicillin

* Sulphonamides

Anticonvulsant:

* phenytoin

*Barbiturates

Anti-tuberculoides

Besides those Aspirin,Naproxen,Allopurinol & others

Some physical factors are posed for this disease also

* Radiotherapy

* Cold

* Sunlight

Others

-Leukaemia

-Non- Hodgkin lymphoma

-multiple myeloma

-polycythemia 

-collagen disease

-Vasculitides

 

Treatment of Erythema multiforme

 

Erythema multiforme minor :

Symptomatic Rx,

-Antihistamines

-Analgesics (3 to 4 days)

-Topical Steroids

Erythema multiforme major :

  • Symptomatic Rx,

-Antihistamines

-Analgesic (3 to 4days)

-Burow Solution dressing for severe skin disease

-Xylocaine & Diphenhydramine  cream for oral ulcer

-Antibiotics if secondary infection suspected

-Oral antivirals (Acyclovir)10mg/kg/day in divided doses

-Systemic steroid- prednisolone (0.5-1mg/kg/day)

One Comment on “Erythema Multiforme”

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